11
72
Cat. No. | Product Name | Target | Signaling Pathways |
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TP1883 |
[Lys5,MeLeu9,Nle10]-NKA(4-10)
|
Neurokinin receptor | GPCR/G Protein; Neuroscience |
[Lys5,MeLeu9,Nle10]-NKA(4-10) 是高选择性和强效 NK2 受体激动剂,IC50值为 6.1 nM,可诱导大鼠眼底和膀胱收缩,EC50 值分别为 117 和 10 nM。 | |||
T12488 |
Pitavastatin D4
NK-104 D4 |
Others | Others |
Pitavastatin D4 is deuterium labeled Pitavastatin. Pitavastatin is a potent inhibitor of HMG-CoA reductase. | |||
T33693 |
NK 1971
NK 266 orotate,2-(2-(3-Heptyl-4-methyl-2-thiazolin-2-ylidene)methine)-3-heptyl-4-methylthiazolium orotate |
||
NK 1971 is a bioactive chemical. | |||
T7559 |
Neurokinin A(4-10)
神经激肽 A (4-10),Neurokinin A(4-10)(TFA) |
Neurokinin receptor | GPCR/G Protein; Neuroscience |
Neurokinin A(4-10) 是一种速激肽NK2受体激动剂。 | |||
T2539 |
Fingolimod hydrochloride
Fingolimod (FTY720) HCl,FTY720,盐酸芬戈莫德 |
TRP/TRPV Channel; S1P Receptor; PAK; LPL Receptor | Cytoskeletal Signaling; GPCR/G Protein; Membrane transporter/Ion channel |
Fingolimod hydrochloride (FTY720) 是一种新型免疫调节剂,是一种 1-磷酸鞘氨醇(S1P) 拮抗剂,作用于 K562 和 NK 细胞,IC50为 0.033 nM。它诱导 S1P1 的内化,从而抑制 S1P 活性。它被鞘氨醇激酶磷酸化,尤其是被 SK2 磷酸化,从而可与 S1PR1、3、4 和 5 结合 | |||
T75742 |
Neurokinin A(4-10) TFA
|
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Neurokinin A (4-10) TFA 是速激肽NK2受体激动剂。 | |||
T76428 |
(β-Ala8)-Neurokinin A (4-10)
|
||
(β-Ala8)-Neurokinin A (4-10) 是一种神经肽,是一种有效的选择性 NK-2(Neurokinin Receptor) 速激肽受体激动剂。 | |||
T82466 |
Englumafusp alfa
RG6076,CD19-4-1BBL,RO7227166 |
||
Englumafusp alfa (CD19-4-1BBL; RO7227166)是一款由CD19特异性抗体域与人41BBL的三聚体胞外域结合构成的融合蛋白。该化合物能够促进T细胞与NK细胞表面CD19特异性4-1BB的交联作用。 | |||
T76897 | Acasunlimab | ||
Acasunlimab (GEN1046) 是一种双特异性抗体 (bsAb),靶向PD-L1和4-1BB。Acasunlimab 通过有条件的4-1BB 刺激增强 T 细胞和 NK 细胞功能,同时构成性地阻断PD-1/PD-L1抑制轴。Acasunlimab 可用于癌症的研究。 | |||
T81077 |
Substance P(1-4)
|
||
Substance P(1-4)为一有效的神经激肽受体(NK-R)拮抗剂,具有调节正常造血功能并抑制内源性红细胞集落(EEC)形成的能力。 | |||
T76426 |
[Lys5,MeLeu9,Nle10]Neurokinin A(4-10)
|
||
[Lys5,MeLeu9,Nle10]Neurokinin A(4-10) (LMN-NKA),Neurokinin A 的类似物,是一种选择性且有效的 NK2R 激动剂。[Lys5,MeLeu9,Nle10]Neurokinin A(4-10) 具有促运动活性。[Lys5,MeLeu9,Nle10]Neurokinin A(4-10) 可用于研究 NK-2 受体在多种组织平滑肌收缩中的作用。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01086 |
CD244 Protein, Mouse, Recombinant (His)
NK cell type I receptor protein 2B4,Natura... |
Mouse | Human Cells |
Natural killer cell receptor 2B4 (2B4/CD244)is a 66 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 protein family. SLAM family proteins have an extracellular domain (ECD) with two or four Ig-like domains and at least two cytoplasmic immunoreceptor tyrosine-based switch motifs (ITSMs). 2B4 interacts with CD48, while other SLAM family proteins interact in a homophilic manner. The mouse 2B4 cDNA encodes a 397 amino acid (aa) precursor that includes a 19 aa signal sequence, a ... | |||
TMPY-01033 |
IL-32 Protein, Human, Recombinant (isoform alpha, His)
IL-32δ,IL-32beta,IL32,TAIFc,IL-32γ,白介素,IL-32 Protein(isoform... |
Human | HEK293 |
IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active,... | |||
TMPY-05092 |
LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His)
lymphocyte-activation gene 3 |
Cynomolgus | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPY-04730 |
LAG-3 Protein, Human, Recombinant (His)
LAG-3,lymphocyte-activation gene 3,CD223 |
Human | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPY-04939 |
LAG-3 Protein, Human, Recombinant
LAG-3,lymphocyte-activation gene 3,CD223 |
Human | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPY-00418 |
IL-21R Protein, Mouse, Recombinant (His)
interleukin 21 receptor,NILR |
Mouse | HEK293 |
Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R, and NILR, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 4 subfamily. Interleukin-21 (IL-21) belongs to a family of cytokines that bind to a composite receptor consisting of a private receptor (IL-21R) and the common cytokine receptor gamma chain ( gamma(C) ). The IL-21R is discovered as a novel member of the class-I-cytokine-receptor family and... | |||
TMPY-01934 |
IL-21R Protein, Human, Recombinant (His)
CD360,NILR,interleukin 21 receptor |
Human | HEK293 |
Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R, and NILR, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 4 subfamily. Interleukin-21 (IL-21) belongs to a family of cytokines that bind to a composite receptor consisting of a private receptor (IL-21R) and the common cytokine receptor gamma chain ( gamma(C) ). The IL-21R is discovered as a novel member of the class-I-cytokine-receptor family and... | |||
TMPY-05480 |
IL-21R Protein, Human, Recombinant (hFc)
interleukin 21 receptor,CD360,NILR |
Human | HEK293 |
Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R, and NILR, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 4 subfamily. Interleukin-21 (IL-21) belongs to a family of cytokines that bind to a composite receptor consisting of a private receptor (IL-21R) and the common cytokine receptor gamma chain ( gamma(C) ). The IL-21R is discovered as a novel member of the class-I-cytokine-receptor family and... | |||
TMPK-00823 |
VEGF165 Protein, Human, Recombinant (His & Avi)
血管内皮生长因子,RP1-261G23.1,MVCD1,MGC70609,VEGFA,VEGFMGC70609,VPF,... |
Human | HEK293 |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. | |||
TMPJ-00864 |
VEGF165 Protein, Human, Recombinant
Vascular Endothelial Growth Factor Isoform 165,血管内皮生长因子,VEGF... |
Human | Human Cells |
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimul... | |||
TMPY-04040 |
CLEC2D Protein, Rat, Recombinant (hFc)
C-type lectin domain family 2, member D |
Rat | HEK293 |
Lectin-like transcript 1 (LLT1) encoded by CLEC2D gene is a C-type lectin-like molecule interacting with human CD161 (NKR-P1A) receptor expressed by natural killer cells and subsets of T cells. CLEC2D transcripts were detected primarily in hematopoietic cell lines and were found to be co-induced by the same activation signals. Although very low amounts of putative soluble CLEC2D protein isoforms could be produced by transfectants, CLEC2D isoforms 2 and 4 were efficiently expressed. CLEC2D uses g... | |||
TMPJ-00538 |
LILRA3/CD85e Protein, Human, Recombinant (His & Avi), Biotinylated
Leukocyte immunoglobulin-like receptor subfamily A member 3,... |
Human | Human Cells |
Leukocyte immunoglobulin-like receptor subfamily A member 3 is also known as CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4 and Monocyte inhibitory receptor HM43/HM31. In humans, it is encoded by the LILRA3 gene. It acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2.It is detected in B-cells, natural kil... | |||
TMPY-00749 |
FGF-2 Protein, Human, Recombinant
fibroblast growth factor 2 (basic),FGF-2,FGFB,HBGF-2,BFGF |
Human | E. coli |
FGF-2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.5 kDa and the accession number is P09038-4. | |||
TMPJ-01337 |
IL-21R Protein, Mouse, Recombinant (aa 20-236, His)
Nilr,IL-21R,Interleukin-21 receptor,IL-21 receptor,Il21r |
Mouse | Human Cells |
Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. IL-21R is expressed mainly on B cells, NK cells, and activated T cells, but is also found on dendritic cells, alternatively activated macrophages, intestinal lamina propria fibroblasts and epithelial cells, and keratinocytes. Both IL-21 and IL-4 are necessary for efficient B cell IgG1 production and normal germinal center architecture. B cell IL-21 R engagement i... | |||
TMPY-04911 |
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated
vascular endothelial growth factor A,血管内皮生长因子 |
Human,Cynomolgus | HEK293 |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular per... | |||
TMPH-01374 |
Gasdermin-B Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
Precursor of a pore-forming protein that acts as a downstream mediator of granzyme-mediated cell death. This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-B, N-terminal) binds to membranes and forms pores, triggering pyroptosis.; Pore-forming protein produced by cleavage by granzyme A (GZMA), which causes membrane permeabilization and pyroptosis in target cells of cytotoxic T and natural killer (NK) cells. Key downstream medi... | |||
TMPY-03039 |
JAM-B Protein, Rat, Recombinant (hFc)
junctional adhesion molecule 2 |
Rat | HEK293 |
Junctional adhesion molecule B (JAM-B), also known as Junctional adhesion molecule 2 (JAM2), Vascular endothelial junction-associated molecule (VE-JAM), and CD322, is a single-pass type I membrane protein that belongs to the immunoglobulin superfamily. It is prominently expressed on high endothelial venules. expression to be restricted to the high endothelial venule of tonsil and lymph nodes. The localization to the endothelium of arterioles in and around inflammatory and tumor foci. JAM-B can f... | |||
TMPY-01575 |
JAM-B Protein, Mouse, Recombinant (His)
junctional adhesion molecule 2,2410167M24R... |
Mouse | HEK293 |
Junctional adhesion molecule B (JAM-B), also known as Junctional adhesion molecule 2 (JAM2), Vascular endothelial junction-associated molecule (VE-JAM), and CD322, is a single-pass type I membrane protein that belongs to the immunoglobulin superfamily. It is prominently expressed on high endothelial venules. expression to be restricted to the high endothelial venule of tonsil and lymph nodes. The localization to the endothelium of arterioles in and around inflammatory and tumor foci. JAM-B can f... | |||
TMPJ-00893 |
IgG2a Protein, Rat, Recombinant
Ig γ-2A chain C region,Ig gamma-2A chain C region,Igg-2a |
Rat | Human Cells |
Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains—two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78% amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and C... | |||
TMPJ-00321 |
LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated
Lymphocyte activation gene 3 protein,CD223,LAG-3,Protein FDC... |
Human | Human Cells |
Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. LAG3 is involved in lymphocyte activation and can bind to HLA class-II antigens. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells and acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells throug... | |||
TMPJ-00141 |
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc)
4-1BB ligand receptor,CD137,CDw137,ILA,TNFRSF9,T-ce... |
Cynomolgus | Human Cells |
Tumor necrosis factor receptor superfamily member 9(TNFRSF9), also known as CD137 and 4-1BB, is an inducible T cell surface protein belonging to the tumor necrosis factor receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. CD137 is expressed by mesenchymal cells, including endothelial cells, chondrocytes, and cells of the central nervous system. CD137 is also broadly expressed by... | |||
TMPY-04731 |
LAG-3 Protein, Human, Recombinant (mFc)
lymphocyte-activation gene 3,CD223,LAG-3 |
Human | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPJ-00142 |
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His)
CDw137,ILA,4-1BB ligand receptor,T-cell antigen |
Cynomolgus | Human Cells |
Tumor necrosis factor receptor superfamily member 9(TNFRSF9), also known as CD137 and 4-1BB, is an inducible T cell surface protein belonging to the tumor necrosis factor receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. CD137 is expressed by mesenchymal cells, including endothelial cells, chondrocytes, and cells of the central nervous system. CD137 is also broadly expressed by... | |||
TMPY-01793 |
JAM-B Protein, Mouse, Recombinant (hFc)
1110002N23Rik,Jcam2,VE-JAM,2410167M24Rik,j... |
Mouse | HEK293 |
Junctional adhesion molecule B (JAM-B), also known as Junctional adhesion molecule 2 (JAM2), Vascular endothelial junction-associated molecule (VE-JAM), and CD322, is a single-pass type I membrane protein that belongs to the immunoglobulin superfamily. It is prominently expressed on high endothelial venules. expression to be restricted to the high endothelial venule of tonsil and lymph nodes. The localization to the endothelium of arterioles in and around inflammatory and tumor foci. JAM-B can f... | |||
TMPY-03040 |
JAM-B Protein, Rat, Recombinant (His)
junctional adhesion molecule 2 |
Rat | HEK293 |
Junctional adhesion molecule B (JAM-B), also known as Junctional adhesion molecule 2 (JAM2), Vascular endothelial junction-associated molecule (VE-JAM), and CD322, is a single-pass type I membrane protein that belongs to the immunoglobulin superfamily. It is prominently expressed on high endothelial venules. expression to be restricted to the high endothelial venule of tonsil and lymph nodes. The localization to the endothelium of arterioles in and around inflammatory and tumor foci. JAM-B can f... | |||
TMPY-05746 |
LAG-3 Protein, Mouse, Recombinant
lymphocyte-activation gene 3,LAG-3,Ly66,CD223 |
Mouse | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPY-04612 |
LAG-3 Protein, Mouse, Recombinant (His)
LAG-3,Ly66,lymphocyte-activation gene 3,CD223 |
Mouse | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPJ-01421 |
LAG-3 Protein, Cynomolgus, Recombinant (hFc)
LAG-3,Protein FDC,Lymphocyte activation gene 3 protein,CD223... |
Cynomolgus | Human Cells |
Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. LAG3 is involved in lymphocyte activation and can bind to HLA class-II antigens. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells and acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells throug... | |||
TMPY-04528 |
LAG-3 Protein, Human, Recombinant (hFc)
lymphocyte-activation gene 3,CD223,LAG-3 |
Human | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPY-01348 |
CD200R4 Protein, Mouse, Recombinant (His)
Cd200r4,CD200 receptor 4,F630107N04 |
Mouse | HEK293 |
Cell surface glycoprotein CD2 receptor 4, also known as Cell surface glycoprotein OX2 receptor 4, CD2 cell surface glycoprotein receptor-like 4, CD2RLa, and CD2R4, is a single-pass type I membrane protein which belongs to theCD2R family. CD2 (OX2) is a cell surface glycoprotein that interacts with a structurally related receptor (CD2R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. In mouse there are up to five genes related to CD2R w... | |||
TMPY-06931 |
LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated
lymphocyte-activation gene 3,CD223,LAG-3 |
Human | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPJ-00070 |
IL-18 Protein, Human, Recombinant (His)
GIF,IL-1 γ,白细胞介素,Iboctadekin,Interleukin-18,Interferon γ-ind... |
Human | Human Cells |
Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After... | |||
TMPY-03759 |
LAG-3 Protein, Rat, Recombinant (His)
lymphocyte-activation gene 3 |
Rat | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPY-01404 |
CD200R4 Protein, Mouse, Recombinant (hFc)
CD200 receptor 4,F630107N04Rik,Cd200r4... |
Mouse | HEK293 |
Cell surface glycoprotein CD2 receptor 4, also known as Cell surface glycoprotein OX2 receptor 4, CD2 cell surface glycoprotein receptor-like 4, CD2RLa, and CD2R4, is a single-pass type I membrane protein which belongs to theCD2R family. CD2 (OX2) is a cell surface glycoprotein that interacts with a structurally related receptor (CD2R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. In mouse there are up to five genes related to CD2R w... | |||
TMPY-05130 |
LAG-3 Protein, Human, Recombinant, Biotinylated
lymphocyte-activation gene 3,CD223,LAG-3 |
Human | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPY-04611 |
LAG-3 Protein, Mouse, Recombinant (hFc)
lymphocyte-activation gene 3,Ly66,LAG-3,CD223 |
Mouse | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPH-01526 |
KMT2E Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
Associates with chromatin regions downstream of transcriptional start sites of active genes and thus regulates gene transcription. Chromatin interaction is mediated via the binding to tri-methylated histone H3 at 'Lys-4' (H3K4me3). Key regulator of hematopoiesis involved in terminal myeloid differentiation and in the regulation of hematopoietic stem cell (HSCs) self-renewal by a mechanism that involves DNA methylation. Also acts as an important cell cycle regulator, participating in cell cycle r... | |||
TMPY-00260 |
IL-21R Protein, Cynomolgus, Rhesus, Recombinant (hFc)
interleukin 21 receptor |
Cynomolgus,Rhesus | HEK293 |
Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R, and NILR, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 4 subfamily. Interleukin-21 (IL-21) belongs to a family of cytokines that bind to a composite receptor consisting of a private receptor (IL-21R) and the common cytokine receptor gamma chain ( gamma(C) ). The IL-21R is discovered as a novel member of the class-I-cytokine-receptor family and... | |||
TMPY-06950 |
IL-21R Protein, Human, Recombinant (His & Avi), Biotinylated
CD360,NILR,interleukin 21 receptor |
Human | HEK293 |
Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R, and NILR, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 4 subfamily. Interleukin-21 (IL-21) belongs to a family of cytokines that bind to a composite receptor consisting of a private receptor (IL-21R) and the common cytokine receptor gamma chain ( gamma(C) ). The IL-21R is discovered as a novel member of the class-I-cytokine-receptor family and... | |||
TMPY-04610 |
IL-21R Protein, Mouse, Recombinant (hFc)
NILR,interleukin 21 receptor |
Mouse | HEK293 |
Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R, and NILR, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 4 subfamily. Interleukin-21 (IL-21) belongs to a family of cytokines that bind to a composite receptor consisting of a private receptor (IL-21R) and the common cytokine receptor gamma chain ( gamma(C) ). The IL-21R is discovered as a novel member of the class-I-cytokine-receptor family and... | |||
TMPJ-01056 |
IL-18 Protein, Mouse, Recombinant (His)
Interferon γ-inducing factor,Interleukin-1 gamma,Igif,IL-1 g... |
Mouse | E. coli |
Interleukin-18 (IL-18)is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63% and 91% amino acid sequence identity with mouse and rat IL-18, respectively. IL-18 binds to the widely expressed IL-18 R alpha which recruits IL-18 R beta to form the signaling receptor complex. Its bioactivity is negatively regulated by interactions with IL-18 binding proteins... | |||
TMPY-04628 |
IL-21R Protein, Rat, Recombinant (mFc)
interleukin 21 receptor |
Rat | HEK293 |
Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R, and NILR, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 4 subfamily. Interleukin-21 (IL-21) belongs to a family of cytokines that bind to a composite receptor consisting of a private receptor (IL-21R) and the common cytokine receptor gamma chain ( gamma(C) ). The IL-21R is discovered as a novel member of the class-I-cytokine-receptor family and... | |||
TMPY-04106 |
IL-21R Protein, Cynomolgus, Recombinant (His)
白细胞介素,白介素,interleukin 21 receptor |
Cynomolgus | HEK293 |
Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R, and NILR, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 4 subfamily. Interleukin-21 (IL-21) belongs to a family of cytokines that bind to a composite receptor consisting of a private receptor (IL-21R) and the common cytokine receptor gamma chain ( gamma(C) ). The IL-21R is discovered as a novel member of the class-I-cytokine-receptor family and... | |||
TMPY-02995 |
IL-21R Protein, Rat, Recombinant (His)
interleukin 21 receptor |
Rat | HEK293 |
Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R, and NILR, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 4 subfamily. Interleukin-21 (IL-21) belongs to a family of cytokines that bind to a composite receptor consisting of a private receptor (IL-21R) and the common cytokine receptor gamma chain ( gamma(C) ). The IL-21R is discovered as a novel member of the class-I-cytokine-receptor family and... | |||
TMPH-01606 |
BAG6 Protein, Human, Recombinant (His & Myc)
BAG-6,Protein G3,BAG family molecular chaperone regulator 6,... |
Human | Baculovirus |
ATP-independent molecular chaperone preventing the aggregation of misfolded and hydrophobic patches-containing proteins. Functions as part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, which maintains these client proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The BAG6/BAT3 complex is involved in the post-translational delivery ... | |||
TMPH-01605 |
BAG6 Protein, Human, Recombinant (E. coli, His & Myc)
BAT3,BAG6,HLA-B-associated transcript 3,BCL2-associated atha... |
Human | E. coli |
ATP-independent molecular chaperone preventing the aggregation of misfolded and hydrophobic patches-containing proteins. Functions as part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, which maintains these client proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The BAG6/BAT3 complex is involved in the post-translational delivery ... | |||
TMPK-00423 |
CD45 Protein, Human, Recombinant (His & Avi)
CD45R,LY5,EC 3.1.3.48,B220,CD45,T... |
Human | HEK293 |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. | |||
TMPY-04471 |
APEG1 Protein, Human, Recombinant (His)
SPEG complex locus,BPEG,SPEGalpha,SPEGβ,APEG-1,SPEGbeta,APEG... |
Human | E. coli |
Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr protein kinase family. SPEG / APEG-1 contains two fibronectin type-III domains, nine Ig-like (immunoglobulin-like) domains, two protein kinase domains. Isoform 1 of SPEG is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 of SPEG is predominantly expre... | |||
TMPY-05598 |
Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated
SIGLEC2,SIGLEC-2,CD22 molecule |
Human | HEK293 |
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. In addition to its potential role as a mediator of intercellular interactions, signal transduction through CD22 can activate B cells and modulate antigen receptor signaling in vitro. ... | |||
TMPJ-01333 |
TEM8/ANTXR1 Protein, Human, Recombinant (His)
ATR,ANTXR1,TEM8,Tumor Endothelial Marker 8,Anthrax Toxin Rec... |
Human | Human Cells |
Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It ... | |||
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